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Eldepryl Medication - Uses & Side Effects

Eldepryl medicine helps to increase or extend the effects of levodopa; carbidopa, and it may slow the progression of Parkinson's disease. It is also used when sinemet no longer seems to be working well. If you will use eldepryl alone, then it has no effect. Because it works only in combination with levodopa.

Eldepryl Dosage

  • The recommended dose of Eldepryl is 10 milligrams per day divided into 2 smaller doses of 5 milligrams each, taken at breakfast and lunch.
  • There is no evidence of additional benefit from higher doses, and they increase the risk of side effects.
  • The use of Eldepryl in children has not been evaluated.

Uses of Eldepryl

  • Selegiline was significantly superior to placebo on all three principal outcome measures employed: change from baseline in daily levodopa/carbidopa dose, the amount of off time, and patient self-rating of treatment success.
  • Beneficial effects were also observed on other measures of treatment success.

Side Effects of Eldepryl

Side effects that you should report to your prescriber or health care professional as soon as possible:

.black, tarry stools
.changes in behavior: mood swings, irritability, confusion, agitation
.chest pain
.headaches
.lightheadedness or fainting spells; loss of balance
.muscle or neck stiffness or spasms
.slow, fast, or irregular heartbeat
.spasms of the head, face, arms, or leg
.dry mouth
.loss of appetite, weight loss
.muscle aches or pains
.vomiting
.ringing in the ears

Warnings and precautions before taking Eldepryl:

  • Do not use Eldepryl if you are also taking meperidine (Demerol).
  • Before using this medicine, tell your doctor if you have heart disease, seizures, or dizzy spells.
  • If you combine eldepryl with tricyclic antidepressants such as elavil and tofranil, then you may suffer a severe reaction. So you should wait at least 14 days after taking eldepryl before beginning therapy with any of these drugs.

Drug Interaction:-

Be sure to tell your doctor what medicines you are taking, including:

  • tricyclic antidepressants
  • other MAO inhibitors
  • dextromethorphan; sumatriptan; bethanidine
  • indoramin
  • buspirone
  • levodopa
  • certain sympathomimetics found in over-the-counter cold remedies and asthma inhalers
  • insulin and oral antidiabetic drugs
  • sedatives and drugs used to aid sleep
  • drugs used for blood pressure
Overdose

Symptoms of MAO inhibitor overdose may include:
Agitation, chest pain, clammy skin, coma, convulsions, dizziness, drowsiness, extremely high fever, faintness, fast and irregular pulse, hallucinations, headache, high blood pressure, hyperactivity, inability to breathe, irritability, lockjaw, low blood pressure, shallow breathing, spasm of the entire body, sweating.


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